Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.36 |
| ▸ | CHRNG | P07510 | 2/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115490 | 0.79 | HCAR3 (0.42) | HCAR3HCAR2HSD11B1SLC6A3SLC6A4 | |
| SCHEMBL8115288 | 0.77 | KMT2A (0.40) | HSD11B1SLC6A3SLC6A4CCR2MEN1 | |
| SCHEMBL8122274 | 0.77 | CFTR (0.39) | HCAR3HCAR2HSD11B1MEN1KMT2A | |
| SCHEMBL8107180 | 0.75 | HCAR2 (0.47) | HCAR2SLC6A3MEN1KMT2AMAPT | |
| SCHEMBL8122728 | 0.75 | HCAR3 (0.47) | HCAR3HCAR2MEN1KMT2AMAPT | |
| SCHEMBL8121636 | 0.69 | SLC6A4 (0.40) | HCAR3HCAR2HSD11B1SLC6A3SLC6A4 | |
| SCHEMBL4472949 | 0.67 | CNR1 (0.49) | HCAR3HCAR2CCR2 | |
| SCHEMBL31332723 | 0.67 | SLC6A4 (0.49) | HCAR3HCAR2HSD11B1SLC6A3SLC6A4 | |
| SCHEMBL15647408 | 0.67 | TAAR1 (0.49) | KMT2A | |
| SCHEMBL31332697 | 0.67 | HSD11B1 (0.40) | HCAR3HCAR2HSD11B1SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |