Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114661 | 0.79 | HSD11B1 (0.36) | KMT2AMAOAMAOBMEN1ALDH1A1 | |
| SCHEMBL8107503 | 0.77 | HCAR3 (0.42) | KMT2AMEN1HSD11B1CCR2SLC6A4 | |
| SCHEMBL8114502 | 0.75 | IGF1R (0.37) | MAPK1NOTUMALDH1A1 | |
| SCHEMBL15874277 | 0.69 | CHEK2 (0.43) | KMT2AMAPK1MAOAMAOBKDM1A | |
| SCHEMBL8117118 | 0.68 | CRHBP (0.40) | ALDH1A1LMNAHDAC4AHRSLC6A4 | |
| SCHEMBL15648040 | 0.66 | TAAR1 (0.37) | MAOBALDH1A1LMNAHDAC4 | |
| SCHEMBL8115490 | 0.66 | HCAR3 (0.42) | KMT2AMAOAMAOBMEN1ALDH1A1 | |
| SCHEMBL3279419 | 0.64 | MAPK1 (0.44) | KMT2AMAPK1MAOAMAOBKDM1A | |
| SCHEMBL8122115 | 0.64 | KMT2A (0.37) | KMT2AMAPK1NOTUMMAOAMAOB | |
| SCHEMBL6401065 | 0.63 | CHRNA1 (0.39) | KMT2AMAPK1ALDH1A1DRD2UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |