Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105461 | 0.75 | CTSK (0.65) | CTSKCTSB | |
| SCHEMBL8099548 | 0.70 | CTSK (0.68) | CTSKCTSBCTSS | |
| SCHEMBL19739032 | 0.69 | ESR2 (0.51) | — | |
| SCHEMBL3454882 | 0.68 | PRMT5 (0.50) | — | |
| SCHEMBL4789866 | 0.68 | CTSK (0.70) | CTSKCTSBCTSLCTSS | |
| SCHEMBL13181749 | 0.67 | PRMT5 (0.45) | — | |
| SCHEMBL4789293 | 0.67 | CTSK (0.68) | CTSKCTSBCTSS | |
| SCHEMBL8106184 | 0.67 | CTSK (0.68) | CTSKCTSBCTSS | |
| SCHEMBL8100198 | 0.66 | CTSK (0.69) | CTSKCTSBCTSS | |
| SCHEMBL4787930 | 0.66 | CTSK (0.69) | CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001128-A1 | 1,2-CYCL0HEXANE DICARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |