Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.46 |
| ▸ | CPN1 | P15169 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | CPA3 | P15088 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757009 | 1.00 | MMP2 (0.48) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL4603751 | 0.96 | MMP2 (0.51) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL4603755 | 0.96 | MMP2 (0.51) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL9208253 | 0.94 | MMP2 (0.50) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL2856572 | 0.94 | MMP2 (0.50) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL7279987 | 0.91 | CPB2 (0.48) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL7279991 | 0.91 | CPB2 (0.48) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL5073973 | 0.82 | CPB2 (0.42) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL5073981 | 0.82 | CPB2 (0.42) | MMP2MMP9MMP12CPB2CPN1 | |
| SCHEMBL31109109 | 0.82 | LTA4H (0.48) | MMP2MMP9MMP12CPB2CPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-04-19 | — | — | EP | disclosed |
| WO-1999001428-A1 | HYDRAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-14 | — | — | WO | disclosed |
| EP-0763013-A1 | HYDROXYLAMINE DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033709-A1 | HYDROXYLAMINE DERIVATIVES AND THEIR USE AS METALLOPROTEINASE INHIBITING AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1995-12-14 | — | — | WO | disclosed |