Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 11/20 | 0.71 |
| ▸ | NPC1 | O15118 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18074274 | 0.84 | HPGD (1.00) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31030951 | 0.83 | HPGD (0.79) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29237869 | 0.83 | HPGD (0.79) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1578469 | 0.82 | RAB9A (0.83) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9856411 | 0.81 | HPGD (0.63) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8346723 | 0.80 | HPGD (0.74) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9449362 | 0.80 | HPGD (0.74) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31000977 | 0.80 | HPGD (0.74) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1677061 | 0.80 | RAB9A (1.00) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3591703 | 0.80 | HPGD (0.74) | HPGDNPSR1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0874805-B1 | PHENYLACETAMIDE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2000-09-20 | — | — | EP | disclosed |
| US-5973201-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-10-26 | — | — | US | disclosed |
| EP-0874805-A1 | PHENYLACETAMIDE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 1998-11-04 | — | — | EP | disclosed |
| WO-1997021668-A1 | PHENYLACETAMIDE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1997-06-19 | — | — | WO | disclosed |