Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 10/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856191 | 0.83 | NPC1 (0.64) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL8107829 | 0.81 | HPGD (0.73) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL10797893 | 0.81 | HPGD (0.68) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL18074274 | 0.78 | HPGD (1.00) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL29237869 | 0.76 | HPGD (0.79) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL31030951 | 0.76 | HPGD (0.79) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL1578469 | 0.76 | RAB9A (0.83) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL17334629 | 0.76 | HPGD (0.73) | HPGDNPSR1RAB9ANPC1L3MBTL1 | |
| SCHEMBL10789684 | 0.75 | LTA4H (0.44) | HPGDRAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL8346723 | 0.74 | HPGD (0.74) | HPGDNPSR1RAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037991-A | Insecticides | SANDOZ LTD. (CH) | 1991-08-06 | — | — | US | disclosed |
| US-4968829-A | ANTHELMINTICS, PARASITICIDES, NEMATOCIDES | SANDOZ LTD. (CH) | 1990-11-06 | — | — | US | disclosed |
| US-4697033-A | INSECTICIDES | SANDOZ LTD. (CH) | 1987-09-29 | — | — | US | disclosed |