Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.50 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14561890 | 0.87 | GAA (0.56) | GAATSHRMEN1KMT2AHRH3 | |
| SCHEMBL100560 | 0.86 | TSHR (0.63) | SAE1UBA2TSHRPOLBMEN1 | |
| SCHEMBL7613307 | 0.81 | POLB (0.60) | POLBMEN1KMT2A | |
| SCHEMBL16276047 | 0.80 | TSHR (0.63) | TSHRPOLBMEN1LMNAKMT2A | |
| SCHEMBL8107929 | 0.80 | SAE1 (0.46) | GAASAE1UBA2TSHRPOLB | |
| SCHEMBL14557542 | 0.80 | GAA (0.61) | GAATSHRPOLBLMNA | |
| SCHEMBL8616896 | 0.79 | POLB (0.59) | GAASAE1UBA2TSHRPOLB | |
| SCHEMBL7616725 | 0.78 | GAA (0.59) | GAATSHRPOLBMEN1LMNA | |
| SCHEMBL8101857 | 0.78 | GAA (0.59) | GAA | |
| SCHEMBL11860609 | 0.78 | TSHR (0.75) | GAATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | claimed |
| US-6121323-A | LIPOXYGENASE INHIBITOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |