Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.46 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19996522 | 0.84 | MAPT (0.53) | SAE1UBA2TSHRLMNAKMT2A | |
| SCHEMBL8109468 | 0.83 | SAE1 (0.44) | SAE1UBA2TSHRLMNAKMT2A | |
| SCHEMBL7609936 | 0.83 | NPC1 (0.61) | POLBHPGDSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7616604 | 0.81 | MEN1 (0.49) | LMNAKMT2APOLBMEN1HTT | |
| SCHEMBL9067959 | 0.81 | MEN1 (0.56) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL7608931 | 0.80 | MTOR (0.57) | TSHRLMNAKMT2AMEN1HPGD | |
| SCHEMBL8107899 | 0.80 | GAA (0.57) | SAE1UBA2TSHRLMNAKMT2A | |
| SCHEMBL24767416 | 0.80 | TSHR (0.47) | SAE1UBA2TSHRLMNAKMT2A | |
| SCHEMBL7615446 | 0.79 | SLC1A3 (0.51) | KMT2AMEN1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL100560 | 0.78 | TSHR (0.63) | SAE1UBA2TSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | claimed |
| US-6121323-A | LIPOXYGENASE INHIBITOR | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| WO-1999028291-A1 | BISHYDROXYUREAS AS INHIBITORS OF THE 5-LIPOXYGENASE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-06-10 | — | — | WO | disclosed |