Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ACLY | P53396 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.43 |
| ▸ | KDM6B | O15054 | 3/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.41 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4223020 | 0.80 | MEN1 (0.63) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL4217232 | 0.80 | KDM6B (0.61) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL4212950 | 0.80 | ALDH1A1 (0.59) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL5146858 | 0.78 | KDM4C (0.58) | MEN1KMT2AACLYHCAR2KDM6B | |
| SCHEMBL2275929 | 0.78 | KMT2A (0.62) | MEN1KMT2ATDP1ACLYKDM4C | |
| SCHEMBL2275804 | 0.78 | HCAR2 (0.63) | HCAR2KDM6BKDM4CHDAC1KDM4D | |
| SCHEMBL5590930 | 0.77 | LCK (0.55) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL4215640 | 0.77 | MEN1 (0.52) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL14428432 | 0.76 | HCAR2 (0.49) | MEN1RECQLBLMKMT2ATDP1 | |
| SCHEMBL14428910 | 0.76 | KDM6B (0.47) | MEN1RECQLBLMKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |