SCHEMBL4212950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4221921	0.93	ALDH1A1 (0.52)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL4217232	0.88	KDM6B (0.61)	ALDH1A1HPGDHSD17B10L3MBTL1KDM4C
	SCHEMBL4209068	0.81	ACLY (0.77)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL1147582	0.81	KDM4C (0.56)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL7995020	0.81	PLK1 (0.67)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL9688887	0.81	ACLY (0.64)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL4223020	0.81	MEN1 (0.63)	ALDH1A1ACLYMEN1KMT2AMAPT
	SCHEMBL4220608	0.81	ADRA1A (0.46)	ALDH1A1POLBHPGDHSD17B10CTDSP1
	SCHEMBL8107946	0.80	MEN1 (0.48)	KDM4CKDM4EKDM6BKDM4DASPH
	SCHEMBL2691864	0.80	HSD17B10 (0.81)	ALDH1A1POLBHPGDHSD17B10CTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.