Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | FABP2 | P12104 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | PPARD | Q03181 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NAAA | Q02083 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975402 | 0.83 | PPARA (0.60) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL13508328 | 0.79 | CYP1A2 (0.58) | ALDH1A1SMN1; SMN2TMEM97SIGMAR1NPC1 | |
| SCHEMBL3102154 | 0.76 | PPARA (0.64) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL27849569 | 0.76 | PPARA (0.64) | PPARAPPARGFABP2ALDH1A1PPARD | |
| Bezafibrate SCHEMBL5077755 | 0.76 | PPARA (1.00) | PPARAPPARGFABP2ALDH1A1PPARD | |
| Bezafibrate SCHEMBL16299 | 0.76 | PPARA (1.00) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL11589022 | 0.76 | TRPV1 (0.66) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL12203826 | 0.75 | NAAA (0.63) | SMN1; SMN2NPC1NAAARAB9A | |
| Bezafibrate SCHEMBL22364278 | 0.75 | PPARA (0.98) | PPARAPPARGFABP2ALDH1A1PPARD | |
| Bezafibrate SCHEMBL28565716 | 0.75 | PPARA (0.98) | PPARAPPARGFABP2ALDH1A1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121299-A | Modulating inflammation with cytochrome P-450 activators and inhibitors | LOVELACE RESPIRATORY RESEARCH INSTITUTE (US) | 2000-09-19 | — | — | US | disclosed |