Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | FABP2 | P12104 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108550 | 0.83 | PPARA (0.61) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL11363899 | 0.80 | PPARA (0.63) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL5309690 | 0.78 | PPARG (0.49) | PPARAPPARGALDH1A1PRSS1CTSG | |
| Methyl Alcohol SCHEMBL11431127 | 0.77 | PPARA (0.86) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL28440832 | 0.77 | MEN1 (0.52) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL28445143 | 0.76 | PRSS1 (0.62) | ALDH1A1SMN1; SMN2PRSS1CTSGCTRB1 | |
| SCHEMBL16235130 | 0.75 | KMT2A (0.51) | ALDH1A1SMN1; SMN2PRSS1CTSGCTRB1 | |
| SCHEMBL6558046 | 0.75 | PPARA (0.93) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL9119675 | 0.75 | PPARA (0.93) | PPARAPPARGFABP2ALDH1A1PPARD | |
| SCHEMBL31550448 | 0.75 | L3MBTL1 (0.55) | PPARAPPARGALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2014-12-18 | — | — | US | disclosed |
| EP-2782902-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | Fabricant, Jill, S. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078446-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | AGER, BPGM, FOSB | PPARA 287/4885PPARG 157/4885FABP2 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.