Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563288 | 0.82 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL9490606 | 0.68 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL27699115 | 0.66 | FFAR3 (0.40) | — | |
| SCHEMBL14360028 | 0.63 | PTGS1 (0.64) | PSEN1 | |
| SCHEMBL16561549 | 0.60 | TSHR (0.31) | — | |
| SCHEMBL7921660 | 0.58 | PSEN1 (0.39) | PSEN1 | |
| SCHEMBL4778767 | 0.58 | TSHR (0.34) | — | |
| SCHEMBL24802589 | 0.57 | BRD4 (0.37) | — | |
| SCHEMBL18415750 | 0.57 | TSHR (0.33) | — | |
| SCHEMBL7921717 | 0.56 | OPRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136986-A | REACTING SUBSTITUTED ACROLEIN COMPOUND WITH ACRYLATES, ACROLEINS, ACROLEIN ACETALS, ALLYL ALCOHOLS OR ALLYL ETHERS TO GIVE 3,4-DIHYDRO-2H-PYRANS, REACTING WITH ACID, FOLLOWED BY REACTING WITH SUBSTITUETED VINYL KETONE, DEHYDROGENATION | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-24 | — | — | US | disclosed |