Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773564 | 0.88 | KDM4E (0.47) | ADORA2AKDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL7377097 | 0.75 | KDM4E (0.44) | PTGDR2KDM4ELMNAAPEX1ALDH1A1 | |
| SCHEMBL8118964 | 0.74 | PTGDR2 (0.41) | PTGDR2KDM4ELMNAAPEX1HPGD | |
| SCHEMBL7376688 | 0.74 | F2 (0.42) | KDM4ELMNAAPEX1ALDH1A1F2 | |
| SCHEMBL7773815 | 0.73 | F2 (0.62) | PTGDR2LMNAALDH1A1F2PRSS1 | |
| SCHEMBL7772069 | 0.71 | KDM4E (0.45) | KDM4ELMNAHPGDALDH1A1 | |
| SCHEMBL11503765 | 0.68 | LMNA (0.50) | KDM4ELMNAAPEX1HPGD | |
| SCHEMBL8124061 | 0.68 | FPR1 (0.41) | KDM4ELMNACYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4456432 | 0.67 | APEX1 (0.42) | KDM4ELMNAAPEX1ALDH1A1F2 | |
| Propane SCHEMBL8174578 | 0.67 | POLB (0.41) | KDM4ELMNACYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019376-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998031671-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS SYNTHESIS INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 1998-07-23 | — | — | WO | disclosed |