Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789665 | 0.78 | FFAR4 (0.45) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL11875025 | 0.70 | CHRM1 (0.64) | FOLH1BHMTHDAC1HDAC2HDAC8 | |
| SCHEMBL9974590 | 0.70 | BHMT (0.52) | FOLH1BHMTGPR84 | |
| SCHEMBL30066031 | 0.68 | ACE2 (0.45) | BHMTFFAR3HDAC3HDAC1HDAC2 | |
| SCHEMBL276026 | 0.68 | — | — | |
| SCHEMBL7949338 | 0.68 | — | — | |
| SCHEMBL905435 | 0.68 | — | — | |
| SCHEMBL28479095 | 0.68 | CA2 (0.52) | FOLH1BHMTHDAC1HDAC2 | |
| SCHEMBL11694145 | 0.67 | BHMT (0.43) | FOLH1BHMT | |
| Ethane SCHEMBL5187495 | 0.66 | TSHR (0.46) | BHMTFFAR3HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117902-A | 6,8-dimercaptooctanoic acid derivatives substituted at the 6-S and/or 8-S position with the (3-methylthiopropanoyl) radical and pharmaceutical compositions intended for the treatment of cancerous tumors | GALDERMAN RESEARCH & DEVELOPMENT, S.N.C. SOPHIA ABTIPOLIS (FR) | 2000-09-12 | — | — | US | disclosed |