Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10393719 | 0.91 | HTR1A (0.51) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL8109737 | 0.90 | HTR1A (0.53) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL1161574 | 0.87 | PKM (0.49) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL9437718 | 0.84 | ALDH1A1 (0.50) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL5658301 | 0.84 | PKM (0.50) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL9437764 | 0.83 | ALDH1A1 (0.55) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL10981754 | 0.83 | ALDH1A1 (0.49) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| SCHEMBL10081599 | 0.82 | PKM (0.57) | ALDH1A1PKML3MBTL1KDM4EHPGD | |
| SCHEMBL9464160 | 0.82 | KDM4E (0.51) | ALDH1A1PKML3MBTL1HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL10992879 | 0.82 | ALDH1A1 (0.54) | ALDH1A1PKML3MBTL1HTR1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| US-5688820-A | NERVOUS SYSTEM DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5688811-A | PSYCHOLOGICAL DISORDERS; NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-11-18 | — | — | US | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-4558060-A | HYPNOTIC PROPERTIES; ANTI-HEART FAILURE MEDICINE | RIOM LABORATORIES - CERM S.A. (FR) | 1985-12-10 | — | — | US | disclosed |