Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.55 |
| ▸ | FPR2 | P25090 | 3/20 | 0.38 |
| ▸ | FPR1 | P21462 | 2/20 | 0.38 |
| ▸ | F9 | P00740 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108531 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL8109546 | 0.85 | ITGB3 (0.41) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8122589 | 0.85 | ITGB3 (0.42) | ITGB3ITGA2BF9F10PRSS1 | |
| Acetic Acid SCHEMBL9095758 | 0.83 | ITGB3 (0.59) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL7418373 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7418392 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7418384 | 0.83 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL9028803 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL7425930 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BFPR2FPR1F9 | |
| SCHEMBL8115481 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BF9F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691953-B1 | 1-AMIDINOPHENYL-PYRROLIDONES/ PIPERIDINONES AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2000-08-02 | — | — | EP | claimed |