Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD3 | Q99594 | 2/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | UGCG | Q16739 | 2/20 | 0.46 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108207 | 1.00 | TEAD3 (0.54) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL6941768 | 1.00 | TEAD3 (0.54) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL6941703 | 1.00 | TEAD3 (0.54) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL8108121 | 0.99 | TEAD3 (0.55) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL6944485 | 0.99 | TEAD3 (0.55) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL3891265 | 0.94 | TEAD3 (0.60) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL7246438 | 0.94 | TEAD3 (0.60) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL3886147 | 0.91 | LTA4H (0.63) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL8108210 | 0.86 | TEAD3 (0.43) | TEAD3LTA4HKDM4EALDH1A1NPC1 | |
| SCHEMBL27533341 | 0.84 | LTA4H (0.70) | TEAD3LTA4HKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056744-A1 | 6,9-DISUBSTITUTED 2- TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | Aventis Pharmaceuticals Inc. (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043675-A1 | 6,9-DISUBSTITUTED 2-[TRANS-(4- AMINOCYCLOHEXYL) AMINO]PURINES | AVENTIS PHARMACEUTICALS INC. (US) | 1999-09-02 | — | — | WO | disclosed |