Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753905 | 0.80 | TRPV4 (0.52) | PGK1MAOAMAOBCYP11B1CYP11B2 | |
| SCHEMBL8100206 | 0.78 | HSD17B10 (0.33) | HSD17B10HTTTSHRCYP1A1CYP1A2 | |
| SCHEMBL3793217 | 0.74 | PDE7A (0.41) | HSD17B10HTTTSHRCYP1A1CYP1A2 | |
| SCHEMBL1145370 | 0.73 | AHR (0.43) | HSD17B10HTTTSHRCYP1A1CYP1A2 | |
| SCHEMBL25051645 | 0.72 | GABRA1 (0.38) | PGK1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL2783347 | 0.72 | TP53 (0.48) | HSD17B10TSHRCYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL9861993 | 0.70 | TRPV4 (0.34) | PGK1CYP1A1CYP1B1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL31612432 | 0.70 | TP53 (0.46) | HSD17B10TSHRCYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL8772397 | 0.70 | CYP3A4 (0.48) | HSD17B10HTTTSHRCYP1A1CYP1A2 | |
| SCHEMBL12164468 | 0.69 | ALDH1A1 (0.45) | HSD17B10HTTTSHRCYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| CN-1039081-C | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1998-07-15 | — | — | CN | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |