Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109714 | 1.00 | SLC6A9 (0.36) | SLC6A9GPR119NR1I2CACNA1BKCNH2 | |
| SCHEMBL8489163 | 0.87 | MEN1 (0.38) | NR1I2CACNA1B | |
| SCHEMBL8489165 | 0.87 | MEN1 (0.38) | NR1I2CACNA1B | |
| SCHEMBL8491225 | 0.86 | CACNA1B (0.39) | SLC6A9GPR119NR1I2CACNA1BKCNH2 | |
| SCHEMBL8491218 | 0.86 | CACNA1B (0.39) | SLC6A9GPR119NR1I2CACNA1BKCNH2 | |
| SCHEMBL8488965 | 0.84 | VCAM1 (0.39) | GPR119 | |
| SCHEMBL8488966 | 0.84 | VCAM1 (0.39) | GPR119 | |
| SCHEMBL8685732 | 0.83 | HCRTR2 (0.31) | — | |
| SCHEMBL8489149 | 0.83 | HCRTR2 (0.31) | — | |
| SCHEMBL6440301 | 0.80 | MEP1B (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |