Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8109751 | 0.84 | SCN9A (0.38) | SCN9AKDM4EPOLBFPR2PROKR1 | |
| SCHEMBL2238309 | 0.77 | KCNH2 (0.57) | OPRK1KCNH2 | |
| Fumaric Acid SCHEMBL2234450 | 0.72 | KCNH2 (0.59) | OPRK1KCNH2 | |
| Fumaric Acid SCHEMBL2234437 | 0.72 | KCNH2 (0.59) | OPRK1KCNH2 | |
| SCHEMBL26971168 | 0.72 | KDM4E (0.58) | HRH3KDM4EPOLBALDH1A1GAA | |
| SCHEMBL8109750 | 0.71 | MMP1 (0.46) | MMP1HRH3FPR2PROKR1 | |
| SCHEMBL20069052 | 0.69 | HRH3 (0.56) | MMP1HRH3FPR2PROKR1 | |
| SCHEMBL2234446 | 0.68 | KCNH2 (0.41) | MMP1KDM4EFAAHCHRNB2CHRNA4 | |
| SCHEMBL17339936 | 0.66 | FPR2 (0.57) | MMP1HRH3POLBFPR2PROKR1 | |
| SCHEMBL8290762 | 0.65 | KDM4E (0.69) | HRH3KDM4EPOLBALDH1A1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |