Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20069052 | 0.80 | HRH3 (0.56) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL8103918 | 0.80 | OGA (0.48) | HRH3OGA | |
| SCHEMBL17339936 | 0.72 | FPR2 (0.57) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL8109748 | 0.71 | SCN9A (0.41) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL30843204 | 0.70 | FPR2 (0.49) | MMP1FPR2PROKR1HRH3HCRTR1 | |
| SCHEMBL20069665 | 0.70 | MMP1 (0.45) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL7956692 | 0.69 | FPR2 (0.47) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL20147421 | 0.68 | OGA (0.57) | HRH3OGA | |
| Hydrochloric Acid SCHEMBL2774867 | 0.67 | MMP1 (0.54) | MMP1FPR2PROKR1HRH3 | |
| SCHEMBL4051291 | 0.67 | FPR2 (0.47) | MMP1FPR2PROKR1HRH3HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143744-A | Sulfamide-metalloprotease inhibitors | SYNTEX (U.S.A.) INC. (US) | 2000-11-07 | — | — | US | disclosed |