Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749516 | 0.78 | HDAC4 (0.35) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL11993802 | 0.69 | HDAC4 (0.44) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL23116133 | 0.67 | LMNA (0.32) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL7173890 | 0.66 | CRHBP (0.38) | HDAC4CRHBPCRHR2 | |
| SCHEMBL8940386 | 0.66 | CRHBP (0.41) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL31506444 | 0.66 | LMNA (0.45) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL28607882 | 0.64 | CRHBP (0.43) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL5897472 | 0.62 | TAAR1 (0.44) | LMNATSHRHDAC4CRHBPCRHR2 | |
| SCHEMBL30344664 | 0.62 | HDAC4 (0.43) | LMNATSHRHDAC4TAAR1GRIN1 | |
| SCHEMBL1604324 | 0.62 | HDAC4 (0.43) | LMNATSHRHDAC4TAAR1GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-54117026-A | — | — | None | — | — | JP | disclosed |
| US-6160194-A | Soil decontamination using ferric chelates and peroxide | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 2000-12-12 | — | — | US | disclosed |
| US-5232484-A | Aqueous acid solution; mineralization; absence of large concentrations of organic solvents, chloride and sulfate | THE CONNECTICUT AGRICULTURAL EXPERIMENT STATION (US) | 1993-08-03 | — | — | US | disclosed |
| JP-S54117026-A | MITICIDE | NIPPON SODA CO LTD | 1979-09-11 | — | — | JP | disclosed |