Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809393 | 0.85 | CRHBP (0.50) | CRHBPCRHR2HDAC4TSHRMEN1 | |
| SCHEMBL7173890 | 0.74 | CRHBP (0.38) | CRHBPCRHR2HDAC4PTGS2 | |
| SCHEMBL10972198 | 0.69 | CRHBP (0.42) | CRHBPCRHR2HDAC4PTGS2CES2 | |
| SCHEMBL11527286 | 0.69 | HDAC4 (0.39) | CRHBPCRHR2HDAC4 | |
| SCHEMBL8109752 | 0.66 | LMNA (0.36) | CRHBPCRHR2HDAC4TSHRCACNA1C | |
| 1,2-Dichlorobenzene SCHEMBL27801440 | 0.63 | TSHR (0.62) | TSHRCES2CES1ALDH1A1LMNA | |
| SCHEMBL10736169 | 0.62 | — | — | |
| 1,2-Dichlorobenzene SCHEMBL8528441 | 0.61 | TSHR (0.59) | TSHRCES2CES1ALDH1A1TP53 | |
| 1,2-Dichlorobenzene SCHEMBL5147145 | 0.61 | TSHR (0.59) | TSHRCES2CES1ALDH1A1LMNA | |
| 1,2-Dichlorobenzene SCHEMBL27754908 | 0.61 | TSHR (0.59) | TSHRCES2CES1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8048647-A | — | — | None | — | — | JP | disclosed |
| JP-H0848647-A | PRODUCTION OF INDANONE DERIVATIVE | SUMITOMO CHEM CO LTD | 1996-02-20 | — | — | JP | disclosed |