Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 13/20 | 0.58 |
| ▸ | RARG | P13631 | 13/20 | 0.58 |
| ▸ | RARA | P10276 | 12/20 | 0.58 |
| ▸ | RXRA | P19793 | 6/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.44 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907166 | 0.85 | RARB (0.56) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL8101908 | 0.84 | RARB (0.72) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL3456673 | 0.81 | RARB (0.64) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL8116640 | 0.81 | RARA (0.41) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10284325 | 0.80 | RARB (0.60) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL10565430 | 0.80 | RARB (0.70) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL28971886 | 0.79 | RARA (0.51) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL6146438 | 0.78 | RARA (0.51) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL27324962 | 0.77 | RARB (0.66) | RARBRARGRARARXRACYP3A4 | |
| SCHEMBL7414449 | 0.76 | RARB (0.71) | RARBRARGRARARXRACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1285830-A | Pyridylpyrrole derivatives | SANKYO CO (JP) | 2001-02-28 | — | — | CN | disclosed |
| EP-1031572-A1 | PYRIDYLPYRROLE DERIVATIVES | Sankyo Company Limited (JP) | 2000-08-30 | — | — | EP | disclosed |