Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27290683 | 0.76 | CYP1A1 (0.49) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL3148643 | 0.76 | TDP1 (0.55) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL27293211 | 0.76 | ALDH1A1 (0.43) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL6340710 | 0.75 | GABRA1 (0.55) | HSD17B10TSHRGABRA1GABRG2GABRB3 | |
| SCHEMBL3753780 | 0.73 | TTR (0.63) | HSD17B10TSHRGABRA1GABRG2GABRB3 | |
| SCHEMBL3604055 | 0.71 | TRIM24 (0.43) | KMT2ACYP1A1CYP1A2CYP1B1HPGD | |
| SCHEMBL1145370 | 0.69 | AHR (0.43) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL30526797 | 0.69 | TYMS (0.37) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL1920608 | 0.69 | TYMS (0.37) | HSD17B10KMT2AHTTTSHRCYP1A1 | |
| SCHEMBL16421961 | 0.69 | ALDH1A1 (0.52) | KMT2AHTTCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0524018-B1 | Isoxazole herbicides | RHONE POULENC AGRICULTURE (GB) | 2000-10-18 | — | — | EP | disclosed |
| US-5424276-A | Herbicidal 4-acyl-5-pyridylisoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-06-13 | — | — | US | disclosed |
| US-5366957-A | Plant growth regulators | RHONE-POULENC ARGRICULTURE LTD (GB) | 1994-11-22 | — | — | US | disclosed |
| EP-0524018-A1 | Isoxazole herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-01-20 | — | — | EP | disclosed |