Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 7/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 7/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 7/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 7/20 | 0.47 |
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL3414603 | 0.98 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3416954 | 0.98 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL3413247 | 0.98 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL8110 | 0.98 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL2895675 | 0.95 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL11798390 | 0.95 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL7204509 | 0.95 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL20485928 | 0.95 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL10868999 | 0.95 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBXDH | |
| Adenine SCHEMBL1370888 | 0.95 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113039191-B | Nucleotide analogues | 奇异基因组学系统公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-4396372-A2 | AMPLIFICATION OLIGONUCLEOTIDES | Singular Genomics Systems, Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| EP-4396339-A1 | METHODS FOR DIFFERENTIATING MODIFIED NUCLEOBASES | Singular Genomics Systems, Inc. (US) | 2024-07-10 | — | — | EP | disclosed |
| US-20240200041-A1 | Modified Pyrococcus Polymerases and Uses Thereof | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-06-20 | — | — | US | disclosed |
| WO-2024128688-A1 | NOVEL BIOMARKERS FOR DIAGNOSIS OR PROGNOSIS OF INTERSTITIAL CYSTITIS AND USE THEREOF | 사회복지법인 삼성생명공익재단 | 2024-06-20 | — | — | WO | disclosed |
| US-12006540-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-11 | — | — | US | disclosed |
| US-20240182875-A1 | ENGINEERED PYROCOCCUS ENZYMES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-06-06 | — | — | US | disclosed |
| US-11999999-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2024-06-04 | — | — | US | disclosed |
| US-20240174709-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2024-05-30 | — | — | US | disclosed |
| US-11987709-B2 | Silicon containing detectable compounds and uses thereof | Singular Genomics Systems, Inc. (US) | 2024-05-21 | — | — | US | disclosed |
| EP-0642347-A1 | USE OF 2-HALO ADENINE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST CHRONIC MYELOGENOUS LEUKEMIA | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0626853-A1 | USE OF SUBSTITUTED ADENINE DERIVATIVES FOR TREATING MULTIPLE SCLEROSIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-12-07 | — | — | EP | disclosed |
| US-5310732-A | Such as cladribine | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-05-10 | — | — | US | disclosed |
| WO-1993023058-A1 | USE OF 2-HALO ADENINE DERIVATIVES AS THERAPEUTIC AGENTS AGAINST CHRONIC MYELOGENOUS LEUKEMIA | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1993016706-A1 | USE OF SUBSTITUTED ADENINE DERIVATIVES FOR TREATING MULTIPLE SCLEROSIS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-09-02 | — | — | WO | disclosed |
| US-5106837-A | Administering 2-halo-2'-deoxyadenosine such as cladribine; treating autohemolytic anemia | THE SCRIPPS RESEARCH INSTITUTE (US) | 1992-04-21 | — | — | US | disclosed |
| US-5057421-A | Thin film membrane enzyme/coemzyme reactor and method of using same | BRUNSWICK CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0364559-A4 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS | — | 1991-01-09 | — | — | EP | disclosed |
| EP-0364559-A1 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS. | SCRIPPS CLINIC RES (US) | 1990-04-25 | — | — | EP | disclosed |
| WO-1989008658-A1 | SUBSTITUTED ADENINE DERIVATIVES USEFUL AS THERAPEUTIC AGENTS | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11999999-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | POLRMT, RNGTT, MTR | PI4KA 3170/4885PI4K2B 2653/4885PI4K2A 2403/4885 |
| US-12006540-B2 | Synthesis of novel disulfide linker based nucleotides as reversible terminators for DNA sequencing by synthesis | POLRMT, RNGTT, MTR | PI4KA 3170/4885PI4K2B 2653/4885PI4K2A 2403/4885 |
| US-20240174709-A1 | NUCLEOTIDE ANALOGUES | NUDT1, POLN, TYMP | PI4KA 1295/4885PI4K2B 1790/4885PI4K2A 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.