Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789307 | 0.95 | LTA4H (0.60) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL30543010 | 0.85 | TERT (0.53) | TSHRCYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL10772416 | 0.85 | LTA4H (0.54) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL13119751 | 0.85 | LTA4H (0.59) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL15902880 | 0.85 | LTA4H (0.48) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL3791201 | 0.85 | MEN1 (0.63) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL10549494 | 0.85 | LTA4H (0.48) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| SCHEMBL10706723 | 0.84 | TSHR (0.57) | TSHRCYP2C19CYP3A4KMT2AMAOB | |
| SCHEMBL3790523 | 0.83 | LTA4H (0.57) | LTA4HTSHRPGRCYP1A2CYP2C9 | |
| Diphenylether SCHEMBL1118926 | 0.81 | LTA4H (0.71) | LTA4HTSHRPGRCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111212844-B | Dimer compound, material for organic element, organic electroluminescent element, display device, and lighting device | 学校法人关西学院 | 2023-08-25 | — | — | CN | disclosed |
| US-20220396549-A1 | SMALL MOLECULE INHIBITORS OF THE MCL-1 ONCOPROTEIN AND USES THEROF | UNIV MARYLAND (US) | 2022-12-15 | — | — | US | disclosed |
| US-10858316-B2 | Small molecule inhibitors of the MCL-1 oncoprotein and uses thereof | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2020-12-08 | — | — | US | disclosed |
| CN-111212844-A | Polycyclic aromatic dimer compound | 学校法人关西学院 | 2020-05-29 | — | — | CN | disclosed |
| US-20180208554-A1 | Small Molecule Inhibitors of the MCL-1 Oncoprotein and Uses Thereof | UNIVERSITY OF MARYLAND, BALTIMORE | 2018-07-26 | — | — | US | disclosed |
| US-9511059-B2 | Antiviral compounds | HOFFMANN-LA ROCHE INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20150353511-A1 | ANTIVIRAL COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2015-12-10 | — | — | US | disclosed |
| EP-2390241-B1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8598349-B2 | Method for manufacturing conjugated aromatic compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-03 | — | — | US | disclosed |
| EP-2390241-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED | 2011-11-10 | — | — | US | disclosed |
| US-20110256790-A1 | THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL | SAINT-GOBAIN ISOVER (FR) | 2011-10-20 | — | — | US | disclosed |
| WO-2007113327-A2 | FUNGICIDE N-CYCLOPROPYL-SULFONYLAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396549-A1 | SMALL MOLECULE INHIBITORS OF THE MCL-1 ONCOPROTEIN AND USES THEROF | MCL1, TP53, MYC | LTA4H 4031/4885TSHR 4302/4885PGR 4485/4885 |
| US-20110275859-A1 | METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND | C9, H1-10, CYP1A1 | LTA4H 3908/4885TSHR 185/4885PGR 1616/4885 |
| US-10858316-B2 | Small molecule inhibitors of the MCL-1 oncoprotein and uses thereof | MCL1, BCL3, BCL9 | LTA4H 4225/4885TSHR 4479/4885PGR 4485/4885 |
| US-20180208554-A1 | Small Molecule Inhibitors of the MCL-1 Oncoprotein and Uses Thereof | MCL1, BCL3, BCL9 | LTA4H 4225/4885TSHR 4479/4885PGR 4485/4885 |
| US-20150353511-A1 | ANTIVIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | LTA4H 2387/4885TSHR 4602/4885PGR 2943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.