Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786168 | 0.86 | TSHR (0.48) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL13647776 | 0.83 | TSHR (0.68) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL17171621 | 0.83 | HSD17B10 (0.46) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL1753863 | 0.83 | TSHR (0.56) | TSHROPRM1OPRL1ALDH1A1 | |
| SCHEMBL23676957 | 0.83 | TSHR (0.41) | TSHRESR1ESR2 | |
| SCHEMBL17172386 | 0.82 | TSHR (0.44) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL13098673 | 0.82 | TSHR (0.44) | TSHROPRM1OPRL1ALDH1A1ESR1 | |
| SCHEMBL10048527 | 0.81 | TSHR (0.47) | TSHROPRM1OPRL1ALDH1A1 | |
| SCHEMBL17658797 | 0.81 | TSHR (0.54) | TSHRALDH1A1 | |
| SCHEMBL10014286 | 0.80 | TSHR (0.64) | TSHROPRM1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897688-B2 | Amino group-terminal viscosifiers, resultant products and uses thereof | SIKA TECHNOLOGY AG (CH) | 2011-03-01 | — | — | US | disclosed |