Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.60 |
| ▸ | NPY1R | P25929 | 10/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.48 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.48 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.48 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.46 |
| ▸ | NPY4R | P50391 | 6/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.45 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.45 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126399 | 0.86 | MCHR1 (0.55) | MCHR1NPY1RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL7750688 | 0.85 | MCHR1 (0.59) | MCHR1NPY1RNPY5RNPFFR1NPFFR2 | |
| SCHEMBL650331 | 0.81 | NPY1R (0.72) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL4650743 | 0.81 | NPY1R (0.61) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL1766005 | 0.80 | TGM2 (0.50) | MCHR1PADI4PADI2TGM2 | |
| SCHEMBL8118603 | 0.79 | NPY1R (0.52) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL1388701 | 0.78 | NPY1R (0.51) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL7750672 | 0.78 | NPY1R (0.51) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8112493 | 0.78 | TRPV1 (0.57) | NPY1RNPY5RNPFFR1NPFFR2NPY4R | |
| SCHEMBL8639063 | 0.78 | PADI4 (0.65) | MCHR1NPY1RNPY5RPADI4NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |