Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 6/20 | 0.65 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.65 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.44 |
| ▸ | NPY4R | P50391 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112002 | 0.78 | MCHR1 (0.60) | PADI4PADI2MCHR1NPY1RNPY4R | |
| SCHEMBL8639071 | 0.78 | HDAC1 (0.43) | PADI4PADI2 | |
| SCHEMBL10662276 | 0.77 | HDAC1 (0.47) | PADI4PADI2 | |
| SCHEMBL6899864 | 0.77 | NPY1R (0.71) | MCHR1NPY1RNPY4RNPY5R | |
| SCHEMBL7059807 | 0.77 | NPY1R (0.71) | MCHR1NPY1RNPY4RNPY5R | |
| SCHEMBL8526187 | 0.77 | MCHR1 (0.60) | PADI4PADI2MCHR1NPY1RNPY4R | |
| SCHEMBL8587073 | 0.77 | PADI4 (0.57) | PADI4PADI2MCHR1NPY1RTACR1 | |
| SCHEMBL8664607 | 0.77 | HDAC1 (0.44) | PADI4PADI2 | |
| SCHEMBL31186837 | 0.74 | KMT2A (0.57) | TACR1 | |
| SCHEMBL8525686 | 0.73 | NPY1R (0.52) | NPY1RNPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885186-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | Dr. Karl Thomae GmbH (DE) | 1998-12-23 | — | — | EP | claimed |
| WO-1997019911-A1 | AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AND PROCESSES FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1997-06-05 | — | — | WO | claimed |