Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112362 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL21107627 | 1.00 | SMN1; SMN2 (0.34) | SMN1; SMN2HTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL11133978 | 0.81 | HTR2C (0.36) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL6184368 | 0.80 | CTSL (0.44) | MAOBOPRM1 | |
| SCHEMBL4023967 | 0.80 | CTSL (0.44) | MAOBOPRM1 | |
| SCHEMBL6173682 | 0.80 | CTSL (0.44) | MAOBOPRM1 | |
| SCHEMBL4021721 | 0.80 | CTSL (0.44) | MAOBOPRM1 | |
| SCHEMBL4021471 | 0.80 | CTSL (0.44) | MAOBOPRM1 | |
| SCHEMBL4808314 | 0.79 | MAOB (0.35) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL4402453 | 0.78 | PTGS2 (0.36) | HTR2AHTR2CHTR2BMAOBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6124354-A | TREATMENT OF URINARY INCONTINENCE OR IRRITABLE BOWEL SYNDROME | PHARMACIA & UPJOHN AB (SE) | 2000-09-26 | — | — | US | disclosed |