Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537285 | 0.80 | MAPK8 (0.56) | KDM4EALDH1A1PABPC1EIF4HHPGD | |
| SCHEMBL148215 | 0.79 | KMT2A (0.42) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL23760001 | 0.76 | MAPK8 (0.56) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL9534703 | 0.75 | MAPT (0.52) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL11176956 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1PABPC1EIF4HHPGD | |
| SCHEMBL11287041 | 0.74 | TOP2A (0.44) | KDM4EALDH1A1PABPC1EIF4HHPGD | |
| SCHEMBL8138336 | 0.74 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL23606459 | 0.73 | MAPT (0.49) | KDM4EALDH1A1HPGDHSD17B10NR4A2 | |
| SCHEMBL7453380 | 0.72 | L3MBTL1 (0.50) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL10518838 | 0.71 | BRD4 (0.51) | KDM4EALDH1A1PABPC1EIF4HHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0658339-B1 | Process and kit for dyeing hair | BRISTOL MYERS SQUIBB CO (US) | 2000-06-07 | — | — | EP | disclosed |
| EP-0658093-B1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL MYERS SQUIBB CO (US) | 2000-06-07 | — | — | EP | disclosed |
| US-5628799-A | DYE IS A NITROBENZENE SUBSTITUTED WITH AT LEAST ONE NUCLEOPHILIC AMINO GROUP; BUFFER PRESENT; DOPA SPECIES, DYE AND OXIDANT REACT TO FORM MELANIN PRECURSOR WHICH DIFFUSES INTO HAIR TO FORM MELANIN | CLAIROL INCORPORATED (US) | 1997-05-13 | — | — | US | disclosed |
| US-5441542-A | Ferricyanide oxidation of dopa to melamin | CLAIROL INCORPORATED (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0658339-A1 | Process and kit for dyeing hair | Bristol-Myers Squibb Company (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658093-A1 | PROCESS AND KIT FOR DYEING HAIR | Bristol-Myers Squibb Company (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0658093-A4 | PROCESS AND KIT FOR DYEING HAIR. | BRISTOL MYERS SQUIBB CO (US) | 1994-09-23 | — | — | EP | disclosed |
| US-5279617-A | Using melanin precursor; oxidizing dopa compound with a ferricyanide salt | CLAIROL INCORPORATED (US) | 1994-01-18 | — | — | US | disclosed |
| WO-1993005759-A1 | PROCESS AND KIT FOR DYEING HAIR | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-04-01 | — | — | WO | disclosed |