Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113007 | 1.00 | GPR35 (0.45) | GPR35HDAC4HDAC8KCNH2HPGD | |
| Hydrochloric Acid SCHEMBL8318758 | 0.99 | GPR35 (0.45) | GPR35HDAC4HDAC8KCNH2HPGD | |
| SCHEMBL8322665 | 0.98 | HPGD (0.45) | GPR35HDAC4HDAC8KCNH2HPGD | |
| SCHEMBL8322667 | 0.98 | HPGD (0.45) | GPR35HDAC4HDAC8KCNH2HPGD | |
| SCHEMBL8322000 | 0.96 | HDAC4 (0.44) | GPR35HDAC4HDAC8KCNH2HPGD | |
| SCHEMBL8321994 | 0.96 | HDAC4 (0.44) | GPR35HDAC4HDAC8KCNH2HPGD | |
| SCHEMBL10365844 | 0.91 | GPR35 (0.56) | GPR35HDAC4HDAC8HPGDPPARG | |
| SCHEMBL10365841 | 0.91 | GPR35 (0.56) | GPR35HDAC4HDAC8HPGDPPARG | |
| SCHEMBL10365846 | 0.83 | PPARG (0.46) | GPR35HDAC4HDAC8HPGDPPARG | |
| SCHEMBL10365647 | 0.78 | GPR35 (0.60) | GPR35HDAC4HDAC8HPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | claimed |
| EP-0751944-B1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| EP-0751944-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | disclosed |