Sugi Predict

Sugi Predict / Compounds / SCHEMBL8322665

SCHEMBL8322665

SCHEMBL8322665

Cc1oc(-c2ccc(-c3ccccc3)cc2)nc1C(=O)COc1ccc(/C=C2/SC(=O)NC2=O)nc1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 2/20 0.45
▸ GPR35 Q9HC97 1/20 0.44
▸ PTPN1 P18031 2/20 0.43
▸ HDAC4 P56524 10/20 0.43
▸ HDAC8 Q9BY41 7/20 0.43
▸ TARBP2 Q15633 2/20 0.43
▸ KCNH2 Q12809 1/20 0.42
▸ PPARG P37231 2/20 0.41
▸ PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8322667 1.00 HPGD (0.45) HPGDGPR35PTPN1HDAC4HDAC8
SCHEMBL8113013 0.98 GPR35 (0.45) HPGDGPR35PTPN1HDAC4HDAC8
SCHEMBL8113007 0.98 GPR35 (0.45) HPGDGPR35PTPN1HDAC4HDAC8
Hydrochloric Acid SCHEMBL8318758 0.97 GPR35 (0.45) HPGDGPR35PTPN1HDAC4HDAC8
SCHEMBL8322000 0.94 HDAC4 (0.44) HPGDGPR35HDAC4HDAC8KCNH2
SCHEMBL8321994 0.94 HDAC4 (0.44) HPGDGPR35HDAC4HDAC8KCNH2
SCHEMBL10365841 0.90 GPR35 (0.56) HPGDGPR35PTPN1HDAC4HDAC8
SCHEMBL10365844 0.90 GPR35 (0.56) HPGDGPR35PTPN1HDAC4HDAC8
SCHEMBL10365846 0.82 PPARG (0.46) HPGDGPR35HDAC4HDAC8TARBP2
SCHEMBL8323757 0.77 PPARG (0.46) TARBP2PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5955481-A Pyridine type thiazolidines NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-21 — — US claimed