Imidacloprid

Imidacloprid

SCHEMBL9045947

COC.O=[N+]([O-])N=C1NCCN1Cc1ccc(Cl)nc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
CHRNB2 P17787 5/20 0.57
CHRNA4 P43681 5/20 0.57
CHRNA1 P02708 2/20 0.53
CHRNA3 P32297 2/20 0.53
CHRNA7 P36544 2/20 0.53
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidacloprid SCHEMBL29436142 0.95 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL22278 0.95 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL12002532 0.95 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL237917 0.95 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL182289 0.95 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL15474899 0.92 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL15284816 0.90 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL7638837 0.90 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL676764 0.90 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL8113019 0.90 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0455000-B1 Dialkoxymethylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS (JP) 1996-01-31 EP disclosed
EP-0455000-A1 Dialkoxymethylimidazolidine derivatives, preparation thereof, insecticides containing same as an effective ingredient and intermediates therefor MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-11-06 EP disclosed