Imidacloprid

Imidacloprid

SCHEMBL237917

O=[N+]([O-])/N=C1\NCCN1Cc1ccc(Cl)nc1.O=[N+]([O-])/N=C1\NCCN1Cc1ccc(Cl)nc1

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CHRNB2 P17787 5/20 0.61
CHRNA4 P43681 5/20 0.61
CHRNA1 P02708 2/20 0.57
CHRNA3 P32297 2/20 0.57
CHRNA7 P36544 2/20 0.57
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
NPSR1 Q6W5P4 1/20 0.49
CASP6 P55212 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Imidacloprid SCHEMBL22278 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL29436142 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL182289 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL12002532 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL9045947 0.95 ALDH1A1 (0.59) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL15474899 0.94 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
Imidacloprid SCHEMBL15284816 0.94 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL7638837 0.94 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL676764 0.94 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1
SCHEMBL8113019 0.94 CHRNA1 (0.66) ALDH1A1SMN1; SMN2CHRNB2CHRNA4CHRNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116970714-A EST-SSR molecular marker of bemisia tabaci detoxification metabolism related gene and application 新疆农业科学院植物保护研究所 2023-10-31 CN disclosed
CN-116908338-A Method for simultaneously measuring 110 pesticide residues in various tropical fruits 中国热带农业科学院三亚研究院 2023-10-20 CN disclosed
US-10980235-B2 Insecticidal composition CLARKE MOSQUITO CONTROL PRODUCTS, INC. (US) 2021-04-20 US disclosed
US-20210106007-A1 INSECTICIDAL COMPOSITION CLARKE MOSQUITO CONTROL PRODUCTS, INC. 2021-04-15 US disclosed
US-10939683-B2 2021-03-09 US disclosed
CN-112021169-A Cutting seedling production method of cut flower Chinese rose 云南锦苑花卉产业股份有限公司 2020-12-04 CN disclosed
CN-112005807-A Production method of grafted seedlings of cut flower Chinese roses 云南锦苑花卉产业股份有限公司 2020-12-01 CN disclosed
CN-112005808-A Method for producing seedlings of cut-flower Chinese roses 云南锦苑花卉产业股份有限公司 2020-12-01 CN disclosed
CN-109503433-A A kind of modified naphthalene series sulfonate and formaldehyde condensation product and its application 江苏精禾界面科技有限公司 2019-03-22 CN disclosed
EP-3428162-A1 ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF Merial Inc. (US) 2019-01-16 EP disclosed
WO-2011104087-A1 PESTICIDAL MIXTURES CONTAINING ISOXAZOLINE DERIVATIVES AND INSECTICIDE OR NEMATOICIDAL BIOLOGICAL AGENT SYNGENTA PARTICIPATIONS AG (CH) 2011-09-01 WO disclosed
US-20100048397-A1 GABA/Pesticidal Combinations PLANT HEALTH CARE, INC. 2010-02-25 US disclosed
US-5952386-A EXCELLENT INSECTICIDAL ACTIVITY FOR THE CONTROL OF NOXIOUS INSECTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-09-14 US disclosed
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
US-5883262-A INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-16 US disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
US-5869506-A APPLYING TO ACARIDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-09 US disclosed
US-5698702-A INTERMEDIATES FOR INSECTICIDES, ACARICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-12-16 US disclosed
US-5684022-A ANTIFERTILITY AGENT PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10980235-B2 Insecticidal composition SGMS2, SGMS1, ITPR3 ALDH1A1 2691/4885SMN1; SMN2 1726/4885CHRNB2 482/4885
US-20210106007-A1 INSECTICIDAL COMPOSITION SGMS2, SGMS1, ITPR3 ALDH1A1 2691/4885SMN1; SMN2 1726/4885CHRNB2 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.