Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492117 | 0.85 | CA2 (0.45) | KMT2ANPSR1CA2ALDH1A1POLB | |
| SCHEMBL2575447 | 0.83 | KMT2A (0.47) | KMT2ANPSR1ALDH1A1L3MBTL1POLB | |
| SCHEMBL27487172 | 0.83 | KMT2A (0.43) | KMT2ANPSR1ALDH1A1L3MBTL1POLB | |
| SCHEMBL27772766 | 0.82 | KMT2A (0.59) | KMT2ANPSR1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL27584979 | 0.82 | CA2 (0.38) | KMT2ANPSR1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL27502344 | 0.82 | KMT2A (0.42) | KMT2ANPSR1ALDH1A1L3MBTL1POLB | |
| SCHEMBL174224 | 0.80 | KMT2A (0.62) | KMT2AALDH1A1MAPTTSHRCA12 | |
| Acetic Acid SCHEMBL28034204 | 0.80 | KMT2A (0.45) | KMT2ANPSR1CA2ALDH1A1L3MBTL1 | |
| SCHEMBL27586732 | 0.77 | ALOX5 (0.47) | KMT2ANPSR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL29822279 | 0.76 | CA1 (0.46) | KMT2ACA2ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107079921-A | Method for controlling the insect in plant | 安道麦马克西姆有限公司 | 2017-08-22 | — | — | CN | claimed |
| EP-0600836-B1 | Selective herbicidal agent | CIBA GEIGY AG (CH) | 1998-08-05 | — | — | EP | claimed |
| US-5532203-A | SULFONYLUREA MIXTURE | CIBA-GEIGY CORPORATION (US) | 1996-07-02 | — | — | US | claimed |
| US-5529974-A | MIXTURE OF PYRIDYLSULFONYLUREA HERBICIDE, SULFAMOYLPHENYLUREA HERBICIDE ANTAGONIST | CIBA-GEIGY CORPORATION (US) | 1996-06-25 | — | — | US | claimed |
| EP-0626958-A1 | SULFONYLUREAS AS HERBICIDES | CIBA-GEIGY AG (CH) | 1994-12-07 | — | — | EP | claimed |
| WO-1993017016-A1 | SULFONYLUREAS AS HERBICIDES | CIBA-GEIGY AG (CH) | 1993-09-02 | — | — | WO | claimed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | claimed |
| US-10975059-B2 | Small molecule BRD4 modulators for HIV epigenetic regulation | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-04-13 | — | — | US | disclosed |
| CN-111377835-A | Preparation method of sulfamoyl phenylurea safeners | 南京正荣医药化学有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-20190292168-A1 | NOVEL SMALL MOLECULE BRD4 MODULATORS FOR HIV EPIGENETIC REGULATION | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-09-26 | — | — | US | disclosed |
| CN-107079921-A | Method for controlling the insect in plant | 安道麦马克西姆有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-102300844-B | Sulfamoyl-phenyl-ureidobenzamidine derivatives as antimalarial agents | 4SC AG | 2015-03-11 | — | — | CN | disclosed |
| CN-101674727-B | Pyridonecarboxamides crop protection agents containing the same method for production and use thereof | BAYER CROPSCIENCE AG | 2014-06-25 | — | — | CN | disclosed |
| EP-0597807-A1 | Selective herbicidal agent | CIBA-GEIGY AG (CH) | 1994-05-18 | — | — | EP | disclosed |
| WO-1993017016-A1 | SULFONYLUREAS AS HERBICIDES | CIBA-GEIGY AG (CH) | 1993-09-02 | — | — | WO | disclosed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| US-5215570-A | Plant safening agents | CIBA-GEIGY CORPORATION (US) | 1993-06-01 | — | — | US | disclosed |
| EP-0365484-B1 | SULFAMOYL PHENYL UREAS | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0264467-B1 | SULFAMOYL UREA DERIVATES | PPG INDUSTRIES, INC. (US) | 1992-06-24 | — | — | EP | disclosed |
| EP-0365484-A1 | Sulfamoyl phenyl ureas | CIBA-GEIGY AG (CH) | 1990-04-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10975059-B2 | Small molecule BRD4 modulators for HIV epigenetic regulation | BRD4, BICRA, BRD3 | KMT2A 52/4885NPSR1 4503/4885CA2 4871/4885 |
| US-20190292168-A1 | NOVEL SMALL MOLECULE BRD4 MODULATORS FOR HIV EPIGENETIC REGULATION | BRD4, BICRA, BRD3 | KMT2A 56/4885NPSR1 4521/4885CA2 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.