Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | MC4R | P32245 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115694 | 0.80 | SHBG (0.37) | — | |
| SCHEMBL2105356 | 0.79 | PNMT (0.43) | PNMTMC4RKMT2AIDO1TDO2 | |
| SCHEMBL8114777 | 0.78 | ESR1 (0.33) | ALOX15SLC6A2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4378576 | 0.76 | PNMT (0.37) | PNMTMC4RKMT2AIDO1TDO2 | |
| SCHEMBL8118969 | 0.76 | ESR1 (0.33) | KDM4EALOX15SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL650314 | 0.76 | ESR1 (0.33) | KMT2AALOX15L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL6914643 | 0.72 | PNMT (0.47) | PNMTIDO1TDO2DAO | |
| SCHEMBL4381403 | 0.72 | ESR1 (0.34) | KMT2AMEN1 | |
| SCHEMBL8113194 | 0.72 | TAAR1 (0.39) | IDO1SLC6A2SLC6A4CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL1438646 | 0.71 | PNMT (0.46) | PNMTIDO1TDO2DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |