SCHEMBL8113702

SCHEMBL8113702

NC(N)(CO)Oc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
RECQL P46063 1/20 0.41
KDM4E B2RXH2 1/20 0.41
POLB P06746 1/20 0.41
LTA4H P09960 3/20 0.39
TAAR1 Q96RJ0 1/20 0.37
TSHR P16473 2/20 0.36
KCNA3 P22001 1/20 0.36
ALOX15 P16050 1/20 0.35
CA5A P35218 1/20 0.34
CA5B Q9Y2D0 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
KCNN4 O15554 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
GRIN2B Q13224 1/20 0.33
LMNA P02545 1/20 0.33
NR1H2 P55055 1/20 0.33
BAX Q07812 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1757874 0.77 ALDH1A1 (0.41) ALDH1A1RECQLKDM4EPOLBLTA4H
SCHEMBL6670077 0.76 ALDH1A1 (0.44) ALDH1A1RECQLKDM4EPOLBLTA4H
SCHEMBL7143393 0.76 TAAR1 (0.45) ALDH1A1RECQLLTA4HTAAR1KCNA3
SCHEMBL7487008 0.74 ALDH1A1 (0.43) ALDH1A1RECQLKDM4EPOLBLTA4H
SCHEMBL10758629 0.74 ALDH1A1 (0.43) ALDH1A1RECQLKDM4EPOLBLTA4H
SCHEMBL28244808 0.73 ALDH1A1 (0.41) ALDH1A1RECQLKDM4EPOLBLTA4H
SCHEMBL3581753 0.72 SMN1; SMN2 (0.41) ALDH1A1TAAR1TSHRALOX15SMN1; SMN2
SCHEMBL28141859 0.71 CA4 (0.42) ALDH1A1LTA4HTAAR1TSHRKCNA3
SCHEMBL27878294 0.71 LTA4H (0.39) ALDH1A1RECQLLTA4HTAAR1TSHR
Sulfamate SCHEMBL9451431 0.71 CA1 (0.41) ALDH1A1KDM4EPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0252351-A1 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same Wella Aktiengesellschaft (DE) 1988-01-13 EP claimed
EP-1037592-A1 NEW DEVELOPER COMBINATIONS FOR OXIDATION COLOURING AGENTS Henkel Kommanditgesellschaft auf Aktien (DE) 2000-09-27 EP disclosed
WO-1999032068-A2 NEW DEVELOPER COMBINATIONS FOR OXIDATION COLOURING AGENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1999-07-01 WO disclosed