Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049380 | 0.89 | PDE4A (0.40) | PDE4DPDE4APDE4BPDE4CADORA2A | |
| SCHEMBL8114007 | 0.88 | ADORA2A (0.49) | PDE4DPDE4APDE4BPDE4CADORA2A | |
| SCHEMBL8128831 | 0.81 | LMNA (0.39) | PDE4DPDE4APDE4BPDE4CADORA2A | |
| SCHEMBL8114300 | 0.80 | CSNK2A2 (0.43) | PDE4DADORA2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL14516487 | 0.78 | ALDH1A1 (0.38) | ADORA2AALDH1A1KDM4EHPGDBCHE | |
| SCHEMBL8124044 | 0.78 | HSD17B10 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2059204 | 0.77 | TLR7 (0.53) | PDE4DADORA2AALDH1A1KDM4EHPGD | |
| SCHEMBL8113726 | 0.76 | TLR7 (0.52) | PDE4DADORA2AALDH1A1KDM4EHPGD | |
| SCHEMBL7551424 | 0.76 | CHRNE (0.33) | PDE4DADORA2AALDH1A1KDM4ELMNA | |
| SCHEMBL8121668 | 0.76 | ADORA2A (0.46) | ADORA2AALDH1A1KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | claimed |
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | claimed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | claimed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | claimed |
| EP-0708773-B1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING & MFG (US) | 2000-10-04 | — | — | EP | disclosed |
| US-5886006-A | VIRICIDES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-03-23 | — | — | US | disclosed |
| US-5648516-A | INTERFERON BIOSYNTHESIS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| US-5627281-A | CHEMCAL INTERMEDIATES FOR VIRICIDES BY INDUCING SYNTHESIS OF INTERFERONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-05-06 | — | — | US | disclosed |
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5444065-A | Viricides | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-08-22 | — | — | US | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5352784-A | Viricides; immunomodulators | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-10-04 | — | — | US | disclosed |