Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128831 | 0.94 | LMNA (0.39) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8113707 | 0.89 | PDE4D (0.47) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8114007 | 0.79 | ADORA2A (0.49) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9048835 | 0.74 | TLR7 (0.39) | PDE4DADORA2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL9050816 | 0.72 | TLR7 (0.44) | PDE4DADORA2AHSD17B10LMNASMN1; SMN2 | |
| SCHEMBL8114300 | 0.71 | CSNK2A2 (0.43) | PDE4DADORA2AALDH1A1HSD17B10KDM4E | |
| SCHEMBL14516487 | 0.70 | ALDH1A1 (0.38) | ADORA2AALDH1A1KDM4EHPGDBCHE | |
| SCHEMBL8124044 | 0.70 | HSD17B10 (0.44) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL2059204 | 0.69 | TLR7 (0.53) | PDE4DADORA2AALDH1A1KDM4EHPGD | |
| SCHEMBL8120835 | 0.68 | TSHR (0.39) | ALDH1A1HSD17B10KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708773-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002598-A1 | FUSED CYCLOALKYLIMIDAZOPYRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |