Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116054 | 0.87 | ALDH1A1 (0.45) | HSD17B10POLBMAPTKDM4ECYP11B2 | |
| SCHEMBL8107497 | 0.87 | ALDH1A1 (0.42) | HSD17B10POLBMAPTKDM4ECYP11B2 | |
| SCHEMBL8122754 | 0.87 | ALDH1A1 (0.61) | HSD17B10MAPTKDM4EALDH1A1HTT | |
| SCHEMBL12830162 | 0.86 | RAB9A (0.43) | HSD17B10POLBMAPTKDM4ECYP11B2 | |
| SCHEMBL8123515 | 0.85 | ALDH1A1 (0.48) | HSD17B10POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL8124087 | 0.85 | ALDH1A1 (0.51) | HSD17B10MAPTKDM4EALDH1A1TDP1 | |
| SCHEMBL8123606 | 0.84 | ALDH1A1 (0.47) | HSD17B10POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL8107319 | 0.83 | HSD17B10 (0.40) | HSD17B10POLBMAPTKDM4ECYP11B2 | |
| SCHEMBL8121384 | 0.83 | ALDH1A1 (0.44) | HSD17B10POLBMAPTKDM4ECYP11B2 | |
| SCHEMBL8121433 | 0.83 | HPGD (0.52) | HSD17B10POLBMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111670182-A | Quinoline derivatives, preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-09-15 | — | — | CN | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124515-A1 | QUINOLINE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 东莞市东阳光农药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |