Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25827593 | 0.81 | CYP2C9 (0.44) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL26721599 | 0.80 | OPRL1 (0.42) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL3420466 | 0.79 | CYP2C9 (0.47) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL3422430 | 0.79 | CYP2C9 (0.47) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL8117361 | 0.78 | CHRNB4 (0.38) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL26721588 | 0.75 | F2 (0.39) | ALDH1A1POLBLMNAMAPTHTT | |
| SCHEMBL22000066 | 0.74 | ALDH1A1 (0.56) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL13361543 | 0.73 | OPRM1 (0.61) | OPRL1OPRM1OPRK1 | |
| SCHEMBL15477998 | 0.73 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAMAPTCYP2C9 | |
| SCHEMBL7226920 | 0.73 | ALDH1A1 (0.39) | ALDH1A1POLBLMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |