Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.40 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420466 | 0.98 | CYP2C9 (0.47) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL3422430 | 0.98 | CYP2C9 (0.47) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL3420479 | 0.86 | MAPT (0.40) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL5449381 | 0.83 | OPRL1 (0.52) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL14045645 | 0.81 | CYP2C9 (0.53) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL8115295 | 0.81 | ALDH1A1 (0.34) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL11868542 | 0.79 | LMNA (0.46) | CYP2C9CYP2C19LMNAMAPTALDH1A1 | |
| SCHEMBL5448789 | 0.79 | ALDH1A1 (0.46) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL9749352 | 0.78 | KMT2A (0.43) | CYP2C9CYP2C19LMNAMAPTALOX15 | |
| SCHEMBL8822655 | 0.78 | ALDH1A1 (0.35) | CYP2C9CYP2C19LMNAMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125792-A1 | MULTI-SUBSTITUTED URACIL DERIVATIVE AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 杭州奥默医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |