Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.57 |
| ▸ | RARA | P10276 | 7/20 | 0.57 |
| ▸ | RXRA | P19793 | 8/20 | 0.49 |
| ▸ | RXRB | P28702 | 8/20 | 0.49 |
| ▸ | RXRG | P48443 | 8/20 | 0.49 |
| ▸ | RARG | P13631 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7706907 | 0.95 | RARA (0.59) | RARBRARARXRARXRBRXRG | |
| SCHEMBL7706900 | 0.87 | RARA (0.62) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8115664 | 0.85 | RARA (0.60) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8116675 | 0.85 | RXRA (0.70) | RARBRARARXRARXRBRXRG | |
| SCHEMBL7710038 | 0.83 | RARA (0.62) | RARBRARARXRARXRBRXRG | |
| SCHEMBL7710046 | 0.81 | RXRA (0.69) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8115004 | 0.81 | RARA (0.69) | RARBRARARXRARXRBRXRG | |
| SCHEMBL7712306 | 0.81 | RARA (0.61) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8118100 | 0.80 | RARA (0.66) | RARBRARARXRARXRBRXRG | |
| SCHEMBL8115662 | 0.80 | RARA (0.58) | RARBRARARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127382-A | AN ANTIPROLIFERATIVE AGENT FOR TREATING SKIN-RELATED DISEASES, AN ANTITUMOR AGENT TREATING CANCER, AN ANTIINFLAMMATORY AGENT TREATING PULMONARY FIBROSIS, ILEITIS, COLITIS AND KROHN'S DISEASE | ALLERGAN SALES, INC. (US) | 2000-10-03 | — | — | US | disclosed |