SCHEMBL8115706

SCHEMBL8115706

CCOCCOC(=O)c1ccccc1NC=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.52
HSD17B10 Q99714 3/20 0.52
ALDH1A1 P00352 7/20 0.51
MAPT P10636 2/20 0.51
CASP3 P42574 1/20 0.51
SENP8 Q96LD8 1/20 0.51
SENP7 Q9BQF6 1/20 0.51
SENP6 Q9GZR1 1/20 0.51
KMT2A Q03164 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
HPGD P15428 1/20 0.48
LMNA P02545 2/20 0.48
TSHR P16473 5/20 0.46
MEN1 O00255 1/20 0.46
RAB9A P51151 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5540387 0.87 ALDH1A1 (0.65) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL5525906 0.87 CASP3 (0.64) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8120935 0.86 TSHR (0.66) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8106862 0.84 TSHR (0.67) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8123582 0.83 TSHR (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8115282 0.82 ALDH1A1 (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8114778 0.82 ALDH1A1 (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8119743 0.82 ALDH1A1 (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8115841 0.82 ALDH1A1 (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3
SCHEMBL8117059 0.82 ALDH1A1 (0.68) KDM4EHSD17B10ALDH1A1MAPTCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed