SCHEMBL8106862

SCHEMBL8106862

CCCCOC(=O)c1ccccc1NC=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
L3MBTL1 Q9Y468 3/20 0.67
TDP1 Q9NUW8 3/20 0.67
CYP3A4 P08684 2/20 0.60
MAPK1 P28482 2/20 0.60
TP53 P04637 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.59
CYP1A2 P05177 2/20 0.59
CYP2C19 P33261 2/20 0.59
ALDH1A1 P00352 10/20 0.59
LMNA P02545 3/20 0.59
HSD17B10 Q99714 3/20 0.58
KDM4E B2RXH2 4/20 0.57
MAPT P10636 2/20 0.57
ADRA1D P25100 1/20 0.53
ADRA1A P35348 1/20 0.53
ADRA1B P35368 1/20 0.53
POLB P06746 1/20 0.52
CASP3 P42574 1/20 0.49
SENP8 Q96LD8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123582 0.96 TSHR (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8114778 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8116376 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8117419 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8117059 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8115841 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8120809 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8119743 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8115282 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8123323 0.94 ALDH1A1 (0.68) TSHRL3MBTL1TDP1CYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO claimed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US claimed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO disclosed
WO-2024182515-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2024-09-06 WO disclosed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US disclosed
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2024-09-05 US disclosed
US-6114546-A Aminomethylene derivatives and ultraviolet absorbent comprising thereof CHEMIPRO KASEI KAISHA, LIMITED (JP) 2000-09-05 US disclosed
EP-0950655-A1 AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME CHEMIPRO KASEI KAISHA, LIMITED (JP) 1999-10-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240292836-A1 AGENTS FOR REPELLING, KNOCKING DOWN, AND/OR KILLING BLOOD-SUCKING ARTHROPODS AND USES THEREOF L3MBTL4, L3MBTL3, L3MBTL1 TSHR 3541/4885L3MBTL1 3/4885TDP1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.