Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.43 |
| ▸ | MPC2 | O95563 | 2/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8116894 | 0.98 | PPARG (0.48) | PPARGPPARATARBP2MPC2CYP2C8 | |
| SCHEMBL8325123 | 0.93 | PPARG (0.44) | PPARGPPARATARBP2MPC2CYP2C8 | |
| SCHEMBL8323065 | 0.92 | PPARG (0.43) | PPARGPPARATARBP2MPC2CYP2C8 | |
| SCHEMBL10367300 | 0.87 | PPARG (0.63) | PPARGPPARAMPC2CYP2C8CYP2C9 | |
| SCHEMBL8116286 | 0.81 | PPARG (0.45) | PPARGPPARAFFAR1CYP3A4RXRA | |
| SCHEMBL8116904 | 0.80 | PPARG (0.52) | PPARGPPARATARBP2FFAR1POLB | |
| SCHEMBL8322667 | 0.77 | HPGD (0.45) | PPARGPPARATARBP2 | |
| SCHEMBL8322665 | 0.77 | HPGD (0.45) | PPARGPPARATARBP2 | |
| SCHEMBL1411928 | 0.75 | PPARG (0.46) | PPARGPPARATARBP2MPC2CYP2C8 | |
| SCHEMBL8113013 | 0.75 | GPR35 (0.45) | PPARGPPARATARBP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | claimed |