Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.56 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.56 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.56 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.56 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.56 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.56 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27597281 | 0.95 | GRIK1 (0.56) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8128055 | 0.77 | CYP3A4 (0.39) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10680326 | 0.74 | GRIA1 (0.67) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8114688 | 0.74 | AKR1B1 (0.50) | — | |
| SCHEMBL8555748 | 0.72 | ALDH1A1 (0.40) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL8559761 | 0.72 | AKR1B1 (0.40) | — | |
| SCHEMBL8118374 | 0.72 | ESPL1 (0.38) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Ym-90K SCHEMBL2049549 | 0.72 | GRIA1 (1.00) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Ym-90K SCHEMBL29798088 | 0.72 | GRIA1 (1.00) | GRIK1GRIA1GRIA2GRIA3GRIA4 | |
| Ym-90K SCHEMBL678466 | 0.71 | GRIA1 (0.97) | GRIK1GRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696288-B1 | QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AG (DE) | 2000-09-20 | — | — | EP | disclosed |
| EP-1002796-A2 | Novel quinoxalindione derivatives, their production and use in medicaments | Schering Aktiengesellschaft (DE) | 2000-05-24 | — | — | EP | disclosed |
| EP-0696288-A1 | QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-14 | — | — | EP | disclosed |
| WO-1994025469-A1 | QUINOXALINDIONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN DRUGS | SCHERING AKTIENGESELLSCHAFT (DE) | 1994-11-10 | — | — | WO | disclosed |